Oral medicine for ED also might not be safe or work well if you have: Very low blood pressure, called hypotension, or uncontrolled high blood pressure, called hypertension. The generic versions are just as effective and much less expensive. It is recommended not to exceed a single 2. If approved, the provider will issue a prescription. There is no clinical evidence of any additive prolongation of the bleeding time when vardenafil is administered with aspirin. Nifedipine: Vardenafil 20 mg, when co-administered with slow-release nifedipine 30 mg or 60 mg once daily, did not affect the relative bioavailability AUC or maximum concentration Cmax of nifedipine, a drug that is metabolized via CYP3A4. Consequently, it is recommended not to exceed a single 2.1 day ago · Viagra is a brand-name prescription drug approved to treat ED. Viagra contains sildenafil, which belongs to a class of phosphodiesterase type 5 (PDE5) inhibitors. Viagra is the well-known brand. · Descriptions. Vardenafil is used to treat men with erectile dysfunction (sexual impotence). It belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Viagra (sildenafil) and cost. Viagra (sildenafil) is a brand-name oral tablet prescribed for erectile dysfunction. The cost of the drug with and without insurance can depend on several factors.