In trials of the drug, individuals taking Cialis saw a significant reduction in the frequency and urgency of urination and improved urine flow. Key facts It usually takes 30 to 60 minutes for tadalafil to work for erectile dysfunction. You can take it at least 30 minutes before you want to have sex. Read more on male sexual health on the Sexual Health Australia site. You can report an adverse event either online, by regular mail or by fax, using the contact information at the bottom of this page. This combination can cause dangerously low blood pressure. It can also interact with many medicines, particularly nitrates used in some types of heart disease and blood pressure medicines.Cialis (tadalafil) is a prescription tablet used for erectile dysfunction and benign prostatic hyperplasia. Learn about dosage, side effects, and more. $ Get free savings. Tadalafil, or generic Cialis, is most commonly used to treat erectile dysfunction (ED). However, it’s also used to treat benign prostatic hyperplasia (BPH) and pulmonary .