If you want around-the-clock ED treatment, daily dosages of Cialis or Tadalafil might be right for you. Cialis tadalafil : This ED medication works with the same principle as Viagra, but lasts up to 36 hours. Learn more in our guide to the safest drug for erectile dysfunction. However, while the prevalence is low, ED medications can very rarely cause serious side effects such as priapism a prolonged, painful erection that can result in permanent erectile dysfunction if not treated immediately. Reduce alcohol consumption: If you frequently experience ED after drinking alcohol, the alcohol may actually be the cause of your erectile dysfunction. It’s available in 25 mg, 50 mg, and mg tablets and lasts up to 18 hours. What is the safest drug for erectile dysfunction?Viagra® is available in three doses: 25 mg, 50 mg and mg. The 25 mg dose is the lowest available dosage of Viagra®, which is only used if you are unable to tolerate . Hims works on a subscription basis; you choose your preferred prescription strength and quantity for monthly delivery. Prices vary greatly depending on which medication you’re . Delivery time: 2–5 business days.