These medications work by inhibiting the action of the enzyme phosphodiesterase type 5, which is found in the smooth muscle tissue of your blood vessels. Have questions? Cialis Dosage for Occasional Use For those of you who like to follow your heart, Cialis is also available to take as needed. Like other ED medications, Cialis works by inhibiting the effects of an enzyme called PDE5, which is responsible for controlling the flow of blood to your penis. As we mentioned above, the price for Cialis and generic tadalafil from your local pharmacy is going to vary based on several factors, like your general location and insurance status. Try having sex without alcohol to see if that solves the problem.The same active ingredient as Cialis at 10% of the cost. Tadalafil is a generic erectile dysfunction medication that’s FDA approved and clinically proven to help men with ED . Hims is a % online platform that connects patients to licensed healthcare professionals in all 50 states. We offer support for conditions ranging from sexual health to skincare, . We worked with our expert medical advisors to determine which ED treatments to offer through our platform – from highly effective as-needed ED treatment .