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Both Cialis and Viagra work quickly. They are PDE5 inhibitors that allow for increased blood flow to the penis, leading to more frequent and harder erections. When oral medications might not be safe Check with your health care team before you take any medicine for erectile dysfunction. Some examples of nitrates are nitroglycerin Nitro-Dur, Nitrostat, others , isosorbide mononitrate Monoket and isosorbide dinitrate Bidil. However, it stays in your body for up to 36 hours and can be taken every 24 hours, so it can work for you constantly.For the as-needed dose, plan to take Cialis at least 30 minutes before sexual activity, but bear in mind it may take as long as 2 hours to take effect. Also, Cialis requires sexual stimulation to.  · But on average, its effects start to lessen 2 to 3 hours after you take a dose. The typical dose for once-daily Cialis for ED is milligrams (mg) to 5 mg. When used as needed for ED, the usual. Cialis is only available by prescription in the United States. Viagra: Additionally, a study from Trusted Source. found that combining L-arginine and sildenafil (Viagra) worked better for.

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