Sildenafil is in a class of medications called phosphodiesterase PDE inhibitors. Cialis stays in your system for up to 36 hours and may provide support for erections during that entire time. You should only be treated with one of these products at a time. Figure 6. The major circulating metabolite results from N-desmethylation of sildenafil, and is itself further metabolized. However, the dosage can range from 25— mg. The pharmacokinetics of sildenafil are dose-proportional over the recommended dose range.VIAGRA is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or mg of sildenafil. Tablets are debossed with PFIZER on one side and VGR25, VGR50 or VGR on the other to indicate the dosage strengths. Close. AdLearn the truth about men’s sex pills and how to achieve optimum results naturally. Male UltraCore is the #1 Rated premium sex pill for maximum enhancing ry Leaders · Watch Video · Fully Equipped · Custom Formulation. Dosage. The dose of Cialis you need will depend on whether you’re taking it daily or as needed. Daily doses are often between and 5 milligrams (mg). The as-needed dose is usually 10 mg but can range from 5–20 mg. The typicaldose of Viagra is 50 mg. However, the dosage can range from 25– mg.