If you are taking tadalafil for erectile dysfunction, your doctor will probably start you on an average dose of tadalafil and increase or decrease your dose depending on your response to the medication. Your doctor will help you decide the best time for you to take tadalafil before sexual activity. People with heart conditions should never take ED medications without consulting a doctor. Finding an online ED provider can feel overwhelming. We considered cost, medications available, and whether generic versions were offered to help reduce costs. In some cases, ED can cause a strain on relationships and impact self-esteem. Tadalafil Cialis is used to treat erectile dysfunction ED, impotence; inability to get or keep an erection , and the symptoms of benign prostatic hyperplasia BPH; an enlarged prostate which include difficulty urinating hesitation, dribbling, weak stream, and incomplete bladder emptying , painful urination, and urinary frequency and urgency in adult men.1. Check your insurance coverage Since Cialis is available as a generic, many insurance plans now cover it (to varying degrees). Generally, Medicare does not cover Cialis, since it’s not considered medically necessary. Drug Facts Common Brands Cialis Drug Class PDE-5 inhibitor Controlled Substance Classification Not a controlled medication Generic Status No lower-cost generic available Availability Prescription only How Tadalafil (Cialis) works Tadalafil (Cialis) is a phosphodiesterase-5 enzyme (PDE-5) inhibitor. It works by blocking PDE Best Low Cost: GoodRx Fastest Delivery: Blink Health: Sesame Sign Up Now Key Specs Cost: Consultation prices vary based on the prescriber; $5 generic prescriptions Medical Consultation Required: Yes Medications Prescribed: Viagra, Cialis, sildenafil, tadalafil Generic offered: Yes Why We Chose It.