How will Cialis be supplied? However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. What important information should you know about Cialis? One advantage Cialis has over Viagra and Levitra is its If you experience chest pain, dizziness, or nausea during sexual activity, call your doctor immediately or get emergency medical treatment, and avoid sexual activity until your doctor tells you otherwise.How Cialis Works. Tadalafil and other PDE5 inhibitors primarily work by inducing muscle relaxation. Tadalafil stops the breakdown of a chemical responsible for relaxing muscles. In ED and PAH, the drug targets muscle cells in blood vessels. When the blood vessel muscle cells relax, this expands the vessel and increases blood flow; this . Tadalafil (Cialis) is taken by mouth either as needed before sexual activity or once daily for erectile dysfunction (ED).It’s also taken once daily to treat symptoms from an enlarged prostate (benign prostatic hyperplasia, or BPH).Tadalafil (Cialis) is available both as brand-name and generic tablets. Common side effects of this medication include . · But on average, its effects start to lessen 2 to 3 hours after you take a dose. The typical dose for once-daily Cialis for ED is milligrams (mg) to 5 mg. When used as needed for ED, the usual.